Multivariate logistic regression was used to calculate each outcome’s adjusted odds ratios and 95% CIs. The primary outcome was live birth, and secondary outcomes included biochemical pregnancy, clinical pregnancy, ectopic pregnancy, miscarriage (early and late), and preterm delivery of singleton (gestational age <37 weeks). Propensity score matching was used to address baseline differences among groups.
The study focused on 3 groups: A (HBsAg positive and hepatitis Be antigen negative), B (HBsAg positive and HBeAg positive), and C (HBsAg negative and HBeAg negative). We investigated the association between HBV infection and pregnancy outcomes among women undergoing their first FET between January 1, 2018, and April 30, 2021, using data from Chengdu Xinan Gynecology Hospital and Chengdu Jinjiang Hospital for Women's and Children’s Health. The study followed the STROBE reporting guideline. A waiver of informed consent was granted because this study used deidentified data. This retrospective cohort study was approved by the Ethics Committees of Chongqing Medical University and Chengdu Xinan Gynecology Hospital.
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